Conolidine’s analgesic outcomes stem from its interaction with non-opioid pain pathways. Contrary to opioids, which bind to µ-opioid receptors during the central nervous process, conolidine modulates alternate molecular targets. A Science Innovations research located that conolidine interacts with the atypical chemokine receptor ACKR3/CXCR7, which regulates opioid peptide availability... https://conolidine-for-knee-pain14671.blogs-service.com/68996283/alternative-natural-pain-relief-to-replace-traditional-painkillers-an-overview